This article describes an initiative to implement an evidence-based early mobility continuum into current ICU culture in 8 hospitals in the United States. This multicenter initiative included process design, culture work, and education. One hundred thirty patients were evaluated, and the results showed substantial utilization of physical therapy within 24 hours of admission and a reduction in ventilator days (3.0 days pre vs. 2.1 days post; p=0.06).